Reports Show This Strain of E. Coli Is Increasing Rapidly

Over the past year we’ve observed that the “simple” E Coli bacterial infection, which represents 80% of all UTIs, is quickly being replaced by this more difficult-to-treat strain known as “ESBL” E Coli.

ESBL stands for Extended-spectrum beta-lactamases.  Beta lactamase is an enzyme produced by the E Coli bacteria to create resistance to beta-lactam antibiotics. ESBLs confer resistance to most of the traditional oral antibiotics.

In 2019, the Center for Disease Control and Prevention (CDC) designated ESBL-producing Enterobacteriaceae as”serious threat” pathogens.

According to this article from the Infectious Disease Society last year, treatment options are limited.  There are only two oral options for ESBL E. Coli cystitis:

  • Fosfomycin (brand name Monurol); and
  • Nitrofurantoin (brand name Macrobid)

D-Mannose, a natural supplement which has traditionally cleared up E. Coli infections, may not be sufficient to clear this new strain. There is a support group on Facebook here where other natural alternatives which may help with ESBL E. Coli are being discussed.

How Will I Know If I Have an ESBL E Coli UTI?

If you have tried D-Mannose and are still suffering from UTI symptoms, you will need to ask your doctor for a urine culture that will specifically look for an ESBL E. Coli.

Do not accept a general diagnosis of E. Coli.    There are new, more sophisticated tests that can quickly identify ESBL strain from the urine culture.

What Are The Chances That My UTI is ESBL E. Coli?

If any of the following risk factors applies to you, you may have this strain:

  • Older age
  • Diabetes mellitus
  • Recurring UTIs
  • Previous treatments with antibiotics
  • Recent surgery or hospitalization
  • Use catheter
  • Nursing home residency
  • Underlying renal or liver pathology
  • International travel (especially Asia and North Africa)